Project Area A

Innate and adaptive immune mechanisms outside of the CNS

 

A01

The impact of nutrition and the gut microbiome in the pathogenesis of multiple sclerosis and its therapeutic implications

PD Dr. Gurumoorthy Krishnamoorthy
MPI für Biochemie
Martinsried

Prof. Dr. Aiden Haghikia
Klinikum der Ruhr-Universität
Bochum

Prof. Dr. Ralf Gold
Klinikum der Ruhr-Universität
Bochum

 

A03

G-protein-coupled receptor signaling in immune cells and endothelial cells: implications for neuroinflammation

Prof. Dr. Nina Wettschureck
Institut für Molekulare Medizin / MPI für Herz- und Lungenforschung
Frankfurt / Bad Nauheim

Prof. Dr. Ari Waisman
Institut für Molekulare Medizin
Mainz

 

A04

Tissue specific regulation of ion channels and immunological responses in multiple sclerosis

Prof. Dr. Bernhard Hemmer
Klinik für Neurologie
TU München

Dr. Klaus Lehmann-Horn
Klinik für Neurologie
TU München

 

A05

Synoptic analysis of adaptive immune reactions in very early multiple sclerosis: Repertoires and target antigens of B and T cells

PD Dr. Klaus Dornmair
Institut für Klinische Neuroimmunologie
LMU München

Prof. Dr. Reinhard Hohlfeld
Institut für Klinische Neuroimmunologie
LMU München

 

A07

A novel IL-6 signaling modality in the direct interaction of immune cells

Prof. Dr. Ari Waisman
Institut für Molekulare Medizin
Mainz

Prof. Dr. Thomas Korn
Neurologische Klinik
TU München

 

A08

Impact of dietary factors on the gut-CNS-axis – implications for CNS autoimmunity

Prof. Dr. Luisa Klotz
Klinik für Neurologie mit Institut für Translationale Neurologie
Münster

Prof. Dr. Dr. Detlef Schuppan
Institut für Translationale Immunologie
Mainz

 

A09

Analysis and therapeutic modification of innate immune regulatory networks controlling T cell responses in multiple sclerosis

Prof. Prof. h.c. Dr. Heinz Wiendl
Klinik für Neurologie mit Institut für Translationale Neurologie
Münster

Dr. Catharina Groß
Klinik für Neurologie mit Institut für Translationale Neurologie
Münster

 

A10

Skin-sensing of environmental factors and ther impact on the development of multiple sclerosis

Prof. Prof. h.c. Dr. Heinz Wiendl
Klinik für Neurologie mit Institut für Translationale Neurologie
Münster

Prof. Dr. Karin Loser
Klinik für Dermatologie
Münster

News

Wed, 20/01/2021
A new study on neurological manifestations of severe COVID-19 reveals nervous system immune deficiency
Patients suffering from COVID-19 can develop concomitant and long-term symptoms in their nervous system. The most common symptom in this context is the loss of the sense of smell and taste, while more severe symptoms such as stroke, cerebral seizures, or meningitis are possible. A team of scientists from the medical faculties at the Universities […]...more
Fri, 15/01/2021
Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity
It has long been acknowledged that multiple sclerosis disease risk is associated with reduced sun-exposure, and subsequent low vitamin D levels. The study by Ostkamp et al. now assessed the relationship between measures of sun exposure and MS severity. For this, the researchers analyzed data of around 2,000 patients from the German NationMS- and the […]...more
Tue, 15/12/2020
Transregio-Cooperative Research Centre „Multiple Sclerosis“ funded for another four years
The Collaborative Research Center 128 “Multiple Sclerosis” is entering its third round. As the German Research Association announced, the major project with locations in Münster, Mainz and Munich will be supported for a further four years (until mid-2024). Speaker Prof. Heinz Wiendl, Co-Spokesperson Prof. Frauke Zipp (Mainz) and other scientists are researching multiple sclerosis – […]...more