Project Area A

Innate and adaptive immune mechanisms outside of the CNS

 

A01

The impact of nutrition and the gut microbiome in the pathogenesis of multiple sclerosis and its therapeutic implications

PD Dr. Gurumoorthy Krishnamoorthy
MPI für Biochemie
Martinsried

Prof. Dr. Aiden Haghikia
Klinikum der Ruhr-Universität
Bochum

Prof. Dr. Ralf Gold
Klinikum der Ruhr-Universität
Bochum

 

A03

G-protein-coupled receptor signaling in immune cells and endothelial cells: implications for neuroinflammation

Prof. Dr. Nina Wettschureck
Institut für Molekulare Medizin / MPI für Herz- und Lungenforschung
Frankfurt / Bad Nauheim

Prof. Dr. Ari Waisman
Institut für Molekulare Medizin
Mainz

 

A04

Tissue specific regulation of ion channels and immunological responses in multiple sclerosis

Prof. Dr. Bernhard Hemmer
Klinik für Neurologie
TU München

Dr. Klaus Lehmann-Horn
Klinik für Neurologie
TU München

 

A05

Synoptic analysis of adaptive immune reactions in very early multiple sclerosis: Repertoires and target antigens of B and T cells

PD Dr. Klaus Dornmair
Institut für Klinische Neuroimmunologie
LMU München

Prof. Dr. Reinhard Hohlfeld
Institut für Klinische Neuroimmunologie
LMU München

 

A07

A novel IL-6 signaling modality in the direct interaction of immune cells

Prof. Dr. Ari Waisman
Institut für Molekulare Medizin
Mainz

Prof. Dr. Thomas Korn
Neurologische Klinik
TU München

 

A08

Impact of dietary factors on the gut-CNS-axis – implications for CNS autoimmunity

Prof. Dr. Luisa Klotz
Klinik für Allgemeine Neurologie
Münster

Prof. Dr. Dr. Detlef Schuppan
Institut für Translationale Immunologie
Mainz

 

A09

Analysis and therapeutic modification of innate immune regulatory networks controlling T cell responses in multiple sclerosis

Prof. Dr. Heinz Wiendl
Klinik für Allgemeine Neurologie
Münster

Dr. Catharina Groß
Klinik für Allgemeine Neurologie
Münster

 

A10

Skin-sensing of environmental factors and ther impact on the development of multiple sclerosis

Prof. Dr. Heinz Wiendl
Klinik für Allgemeine Neurologie
Münster

Prof. Dr. Karin Loser
Klinik für Dermatologie
Münster

News

Tue, 17/10/2017
Three new CRC associates
Muenster / Mainz / Munich. The CRC is proud to welcome three scientists as new associates: Muthuraman Muthuraman (Mainz), Anneli Peters (LMU) and Gerd Meyer zu Hörste (Münster). All three are reputable neuroimmunologists, who add their in-depth knowledge of techniques and concepts to the existing team. Dr. Muthuraman Muthuraman is head of the scientific working group […]...more
Tue, 12/09/2017
Genetically altered mice provide initial evidence that human gut bacteria can trigger multiple sclerosis
Munich. (LMU)  Multiple sclerosis (MS) is the most common inflammatory disease of the central nervous system. There are many indications that MS is an autoimmune disease in which immune cells “accidentally” attack the brain and spinal cord. However, as with other autoimmune diseases, the actual triggers of the autoimmune reaction are still unknown. A new […]...more
Sun, 10/09/2017
SFB researcher acquired Hertie foundation funding
Munich. SFB CRC 128 researcher Dr. Klaus Lehmann-Horn, Department of Neurology, has acquired 396.000€ of funding as part of the framework „MyLab“, which is sponsored by the Hertie foundation. The duration of the project „Antigen-driven affinity maturation of B lymphocytes in meningeal ectopic lymphoid tissue in a model of Multiple Sclerosis“ will be 5 years, […]...more