Welcome to the website for Transregional Collaborative Research Center (CRC) SFB TR-128 Initiating/effector versus regulatory mechanisms in Multiple Sclerosis – progress towards tackling the disease. On this site you will find general information regarding the CRC as well as more specific information about its individual research projects.

Multiple Sclerosis (MS) is the most common chronic inflammatory disease of the central nervous system (CNS) in the western world and it leads to devastating disability in young adults, with only limited treatment options currently available. The socioeconomic burden of this disease is tremendous, since healthcare costs are very high and it affects decisions young patients must make for the rest of their lives. Findings in patients are a complex composite of inflammation (with demyelination, remyelination, axonal/neuronal damage) typically in subcortical, but also cortical, disseminated lesions as well as neurodegeneration. Remissions of clinical relapses point to repair capacities of the CNS, which exhibits strong interindividual and course dependent differences.

Heinz Wiendl

Frauke Zipp


Mon, 18/07/2016
18 July 2016: Nir Gov speaks about cell motility
On the 18 July 2016, Nir Gov from the Faculty of Chemistry in Revohot/Israel will come to Muenster to give a lecture on a “Theoretical model for persistant and oscillatory cell motility”. More information can be found here....more
Wed, 06/07/2016
11 July 2016: Lecture of Christoph Rademacher in Muenster
On the 11 July 2016, Christoph Rademacher from the Max Plack Institute Potsdam will hold a lecture entitled “Ligand-based targeted delivery to C-type lectin receptors on immune cells” as part of the Muenster lecture series “Pioneers of cell dynamics and imaging”, organized by the excellence cluster Cells in Motion. For more information, you can have […]...more
Mon, 04/07/2016
Lecture: Prof. Emmanuel Flamand Roze on 5th July in Mainz
Within the FTN seminar series, Prof. Emmanuel Flammand Roze from the Marie Curie University in Paris has been invited by Prof Sergiu Groppa to talk about “Lateralization of motor control and neurodevelopment: the mirror movements paradigm”. The lecture will be in the lecture hall of building 706, starting at 6:00pm. Download the flyer:...more