Welcome to the website for Transregional Collaborative Research Center (CRC) SFB TR-128 Initiating/effector versus regulatory mechanisms in Multiple Sclerosis – progress towards tackling the disease. On this site you will find general information regarding the CRC as well as more specific information about its individual research projects.

Multiple Sclerosis (MS) is the most common chronic inflammatory disease of the central nervous system (CNS) in the western world and it leads to devastating disability in young adults, with only limited treatment options currently available. The socioeconomic burden of this disease is tremendous, since healthcare costs are very high and it affects decisions young patients must make for the rest of their lives. Findings in patients are a complex composite of inflammation (with demyelination, remyelination, axonal/neuronal damage) typically in subcortical, but also cortical, disseminated lesions as well as neurodegeneration. Remissions of clinical relapses point to repair capacities of the CNS, which exhibits strong interindividual and course dependent differences.

Heinz Wiendl

Frauke Zipp


Thu, 22/02/2018
Cooperation of Th17 and B cells in CNS autoimmunity
Munich. SFB researcher Anneli Peters, project leader at the MPI of Neurobiology and researcher within the SFB 128 elucidates the “Cooperation of Th17 and B cells in CNS autoimmunity” when giving a lecture at the IMPRS lecture series. When?: Thursday, March 1, 2018 at 5.00 pm (s.t.) Where?: Main Lecture Hall, T building, MPI of […]...more
Fri, 16/02/2018
Muenster scientists present their latest research
Muenster.  The Scientific Retreat of the SFB CRC-TR 128 will be held on the 9th and 10th of March 2018. PhD students and young postdocs from all labs of the Department of Neurology and Insititute for Translational Neurology in Münster will give short oral presentations summarizing their main ongoing projects. Sessions will be introduced by […]...more
Fri, 16/02/2018
Cancelled: Ion channels in autoimmune neurodegeneration
Muenster. The lecture entitled “Ion channels in autoimmune neurodegeneration” to be held by SFB-PI Prof. Sven Meuth on Monday, February 26, 2018, 5:00 – 6:30 PM, has tobe cancelled....more