Welcome

Welcome to the website for Transregional Collaborative Research Center (CRC) SFB TR-128 Initiating/effector versus regulatory mechanisms in Multiple Sclerosis – progress towards tackling the disease. On this site you will find general information regarding the CRC as well as more specific information about its individual research projects.

Multiple Sclerosis (MS) is the most common chronic inflammatory disease of the central nervous system (CNS) in the western world and it leads to devastating disability in young adults, with only limited treatment options currently available. The socioeconomic burden of this disease is tremendous, since healthcare costs are very high and it affects decisions young patients must make for the rest of their lives. Findings in patients are a complex composite of inflammation (with demyelination, remyelination, axonal/neuronal damage) typically in subcortical, but also cortical, disseminated lesions as well as neurodegeneration. Remissions of clinical relapses point to repair capacities of the CNS, which exhibits strong interindividual and course dependent differences.

Heinz Wiendl
Spokesperson

Frauke Zipp
Co-Spokesperson

News

Tue, 05/06/2018
21st Meeting on T-Cells, Subsets and Functions
Marburg. SFB-PI Prof. Dr. Tobias Bopp & Prof. Dr. Magdalena Huber are chairing this year’s “21st Meeting on T-Cells, Subsets and Functions“ in Marburg. The two-day conference covers all recent aspects of T cell subsets, including Th1, Zh2, Th17, CD8 NKT and regulatory T cells When?: Thursday, June 21, 12.00 – 8.00 PM and Wednesday, […]...more
Fri, 25/05/2018
SFB/CRC-TR 128 retreat in Munich
Munich. The CRC-TR 128 “Multiple Sclerosis” cordially invites all its members – principal investigators as well as associated scientists and young investigators – to meet for a general scientific update, discussion and exchange at this year’s retreat. In addition to the PI meeting there will be a one-day conference especially for young investigators. When?: Thursday […]...more
Tue, 10/04/2018
Lecture: Environmental influence on the immune system
Mainz. The Research Center for Immunotherapy (FZI) and CRC 1292 are happy to welcome SFB 128 PI Prof. Karin Loser, MD, as a guest lecturer at their immunological seminar. Prof. Loser will talk about “Control of Immune responses by the environment”. When?: Thursday, April 26, 5:00 PM Where? University Medical Center Mainz, building 708, seminar […]...more