Welcome to the website for Transregional Collaborative Research Center (CRC) SFB TR-128 Initiating/effector versus regulatory mechanisms in Multiple Sclerosis – progress towards tackling the disease. On this site you will find general information regarding the CRC as well as more specific information about its individual research projects.

Multiple Sclerosis (MS) is the most common chronic inflammatory disease of the central nervous system (CNS) in the western world and it leads to devastating disability in young adults, with only limited treatment options currently available. The socioeconomic burden of this disease is tremendous, since healthcare costs are very high and it affects decisions young patients must make for the rest of their lives. Findings in patients are a complex composite of inflammation (with demyelination, remyelination, axonal/neuronal damage) typically in subcortical, but also cortical, disseminated lesions as well as neurodegeneration. Remissions of clinical relapses point to repair capacities of the CNS, which exhibits strong interindividual and course dependent differences.

Heinz Wiendl

Frauke Zipp


Mon, 09/01/2017
Prof. Florian Bassermann speaks in Mainz
Mainz. The Molecular Signaling Unit at the Research Center for Immunotherapy (FZI) and the University Cancer Center (UCT) of the University Medical Center, Mainz proudly present 2017´s first Biomedical Research Seminar in Oncology (kindly sponsored by Merck) Speaker: Prof. Dr. Florian Bassermann, III. Medizinische Klinik, Klinikum Rechts der Isar der Technischen Universität München Title: “The […]...more
Wed, 04/01/2017
Lecture: How T cells talk to phagocytes
Muenster. The Department of Neurology welcomes Prof. Dr. Burkhard Becher (Zurich) for a Lecture entitled “Tissue Inflammation: How T cells talk to phagocytes!” Date: January 11th, 2016 Time: 6:15 p.m. Place: Conference Room (05.603), Western Tower, University Clinic Muenster, Albert-Schweitzer-Campus 1, Gebäude A 1, 48149 Münster Prof. Becher is co-chair of the Institute of Experimental […]...more
Wed, 04/01/2017
“Zellkraftwerk´s chipcytometry”
Mainz– The Research Center for Immunotherapy (FZI) Mainz is offering a very special lunch seminar about a new technique: Christoph Enz, Bramsche (Cenibra) will talk about: “Zellkraftwerk´s chipcytometry and how it changes processes and possibilities for biomarker analyses in preclinical and clinical trials” When?: 17.01.2017, 11:30 – 13:00 Where?: UMC, 706, Lecture Hall The analysis […]...more