Welcome

Welcome to the website for Transregional Collaborative Research Center (CRC) SFB TR-128 Initiating/effector versus regulatory mechanisms in Multiple Sclerosis – progress towards tackling the disease. On this site you will find general information regarding the CRC as well as more specific information about its individual research projects.

Multiple Sclerosis (MS) is the most common chronic inflammatory disease of the central nervous system (CNS) in the western world and it leads to devastating disability in young adults, with only limited treatment options currently available. The socioeconomic burden of this disease is tremendous, since healthcare costs are very high and it affects decisions young patients must make for the rest of their lives. Findings in patients are a complex composite of inflammation (with demyelination, remyelination, axonal/neuronal damage) typically in subcortical, but also cortical, disseminated lesions as well as neurodegeneration. Remissions of clinical relapses point to repair capacities of the CNS, which exhibits strong interindividual and course dependent differences.

Heinz Wiendl
Spokesperson

Frauke Zipp
Co-Spokesperson

News

Fri, 31/08/2018
Women in Science Network Conference “Decision Making in Infection and Immunity”
The female scientists invite you to the Women-in-Science Network Conference Münster 2018, co-funded by the SFB TR-128. This conference taking place on November 27 and 28 has two main goals: (1) to present and discuss top-level scientific contributions and (2) to increase visibility, encourage leadership, and provide a strong community for women in science. The […]...more
Tue, 10/07/2018
SFB offers workshop on Bioinformatics
Mainz. SFB Associate Muthuraman Muthuraman cordially invites all members to the “Bioinformatics Workshop” on Monday, September 24, 2018. The one-day event combines lectures on topics such as “Machine learning and statistics”, “Bioinformatics analyses of multi parameter flow cytometry data” and “Computational System Genetics” with a hands-on session. The full program is available here....more
Mon, 05/02/2018
Roland Liblau: “Immune targeting of CNS neurons” – Video available
Münster. On January 31, Prof. Roland  Liblau,  Director of the Pathophysiology Research Center at Toulouse Purpan, gave a lecture on “Immune targeting of CNS neurons: from mouse models to human diseases”. Prof. Liblau is one of the most visible neuroimmunologists worldwide which is why the SFB 128 is proud to make his lecture also available […]...more