News

Thu, 22/06/2017
CSF diagnostics in neurodegenerative diseases
Munich. Prof. Markus Otto from the Department of Neurology Ulm is invited speaker at the neurocolloquium Munich. Prof. Otto is head of the scientific working group on neurochemistry and neurodegeneration at Ulm University and expert on neurochemical diagnosis of neurodegenerative disease (14-3-3, Tau-protein, Abeta-Peptides, S-100B, H-FABP, alpha synuclein) as well as head of a sample […]...more
Wed, 07/06/2017
Mechanisms of neural stem cell homeostasis in human brain organoids
Mainz. Dr. Jay Gopalakrishnan from the University of Cologne is an emerging leader in the field of brain development and microcephaly. He has been invited by SFB scientist Prof. Rajalingam as guest at the joint MSU/FTN seminar and will present his work in a lecture on “Mechanisms of neural stem cell homeostasis in human brain […]...more
Mon, 29/05/2017
International Symposium “Cells in Motion: Pattern formation in space and time”
Muenster. For the second time, the Cluster of Excellence “Cells in Motion” (CiM) hosts an international symposium. In interdisciplinary sessions and talks, international top class scientists will present their current research questions and findings. The list of speakers comprises experts from chemistry, mathematics, physics, biology and medicine, going beyond the boundaries of specialized fields and […]...more

News


CSF diagnostics in neurodegenerative diseases

Thu, 22/06/2017

Munich. Prof. Markus Otto from the Department of Neurology Ulm is invited speaker at the neurocolloquium Munich. Prof. Otto is head of the scientific working group on neurochemistry and neurodegeneration at Ulm University and expert on neurochemical diagnosis of neurodegenerative disease (14-3-3, Tau-protein, Abeta-Peptides, S-100B, H-FABP, alpha synuclein) as well as head of a sample bank of CSF and serum. His talk is entitled “Aktuelles zur Labordiagnose neurodegenerativer Erkrankungen: die Zukunft der Liquordiagnostik liegt im Blut“ and will be held in German.
When? Monday, July 5, 6:00-7:30 PM
Where? Library, 4th floor, Neuro-Kopf-Zentrum, Klinikum rechts der Isar, Ismaninger Str. 22, Munich


Mechanisms of neural stem cell homeostasis in human brain organoids

Wed, 07/06/2017

Mainz. Dr. Jay Gopalakrishnan from the University of Cologne is an emerging leader in the field of brain development and microcephaly. He has been invited by SFB scientist Prof. Rajalingam as guest at the joint MSU/FTN seminar and will present his work in a lecture on “Mechanisms of neural stem cell homeostasis in human brain Organoids”.
When?: Tuesday, June 13, 4:30pm
Where?: seminar room 2, building 708, University Medical Center, Langenbeckstr. 1


International Symposium “Cells in Motion: Pattern formation in space and time”

Mon, 29/05/2017

Muenster. For the second time, the Cluster of Excellence “Cells in Motion” (CiM) hosts an international symposium. In interdisciplinary sessions and talks, international top class scientists will present their current research questions and findings. The list of speakers comprises experts from chemistry, mathematics, physics, biology and medicine, going beyond the boundaries of specialized fields and reflecting the interdisciplinary character of CiM. Topics will range from molecular self-organization, membrane organization as well as cell-matrix and cell-cell interaction to tissue morphogenesis, mechanobiology and imaging technologies. In addition to talks from invited speakers and CiM group leaders, junior scientists from CiM labs – among them scientists from the SFB 128 – will get the opportunity to present their research.
When?: Mon-Wed, September 4-6
Where?: lecture hall GEO1, Heisenbergstraße 2, Münster.
More information


Swedish data on Rituximab – presentation by Fredrik Piehl

Wed, 17/05/2017

Munich. Sweden is the only country where the MS treatment Rituximab is frequently used even if it has not been formally approved. The neuroimmunologist mainly responsible for this fact is MS researcher Fredrik Piehl from Karolinska Institutet in Stockholm/Sweden. His research group provided observational data on Rituximab therapy and will now start a large clinical follow-up trial on this and other MS therapies. He will present his research at the Neurological Colloquium:
When?: Wednesday, May 31, 6:00-7:30 PM
Where?: Library, 4th floor, Neuro-Kopf-Zentrum, Klinikum rechts der Isar, Ismaninger Str. 22, Munich


Hematopoietic stem cell niche and cell signaling

Wed, 17/05/2017

Mainz. Borhane Guezguez (Mainz/Frankfurt/Heidelberg) has recently become head of a scientific working group at UCI. He will present his work in a lecture on “Hematopoietic Stem Cell Niche and Cell Signaling: From Biological Aspects To Therapeutic Perspectives”

Time: Wednesday, 17th of May, 5:15pm
Place: SR2, Building 708, University Medical Center, Langenbeckstr. 1, Mainz


Lecture: MS: Can we develop therapies?

Wed, 17/05/2017

Muenster. The Department of Neurology is happy to announce that Dr. Susan Goelz will give a lecture as part of the Neurological Seminar.

Time: Wednesday, May 17, 6:15pm
Place: Large conference room, Level 05 West in the central clinics building, Albert-Schweitzer-Campus 1, 48149 Muenster

Title of her talk: „Putative pathways leading to neurodegeneration in MS:  Can we develop therapies?”

After her time as a Postdoc, Susan Goelz was working as a scientist and manager in the pharmaceutical industry, first at Biogen (from 1988 on), then at Elan Pharmaceuticals. In her time at Biogen, she was responsible for the development and market introduction / approval process of Interferon-beta (Avonex), which has been one of the most successful MS therapies since its FDA approval in 1995. In addition to her post as a lecturer at Oregon Health and Sciences University, she works as a consultant for pharmaceutical companies and specializes in translational medicine, as well as networking between academia and pharmaceutical industries. She has connections all over the world and expertise in the newest techniques, disease models, and treatment options.


International symposium 2017: SFB junior researchers present their projects

Thu, 20/04/2017

Muenster. For the second time, the Cluster of Excellence “Cells in Motion” hosts an international symposium. In interdisciplinary sessions and talks, international top class scientists will present their current research questions and findings. The list of speakers comprises experts from chemistry, mathematics, physics, biology and medicine, going beyond the boundaries of specialised fields and reflecting the interdisciplinary character of the Cells-in-Motion Cluster of Excellence (CiM). Topics will range from molecular self-organisation, membrane organisation as well as cell-matrix and cell-cell interaction to tissue morphogenesis, mechanobiology and imaging technologies. In addition to talks from invited speakers and CiM group leaders, junior scientists from CiM labs – among them scientists from the SFB 128 – will get the opportunity to present their research.

When?: Mon-Wed,  September 4-6

Where?: lecture hall GEO1, Heisenbergstraße 2, Münster.

Please register until June 30. Participation is free of charge. Junior researchers from CiM labs are encouraged to apply for a poster or short talk presentation until 5 May 2017. Application form


Cardiac regeneration: from Zebrafish to mammals

Thu, 20/04/2017

Muenster. At the lecture series “Piomeers in Cell Dynamic and Imaging” international guests as well as scientists from the Cells-in-Motion Cluster of Excellence and the biomedical Collaborative Research Centres of the University of Münster present their most recent scientific advances in basic and translational research. In April, Felix Engel, Professor for Experimental Renal and Cardiovascular Research at Erlangen University talks about “Cardiac regeneration: from zebrafish to mammals”

When?: Monday, April 24, 5:00 PM

Where?: lecture hall, Institute of Physiological Chemistry and Pathobiochemistry, Waldeyerstraße 15, Münster.


Spotlight on formyl peptide chemoattractant receptors

Thu, 20/04/2017

Muenster. The CRC Breaking Barriers: Immune cells and pathogens at cell / matrix barriers cordially invites interested audience to attend its upcoming Jour-Fixe Meeting. SFB scientists Ursula Rescher and Volker Gerkewill talk about Formyl peptide chemoattractant receptors in leukocyte activation and trans-endothelial migration.

When?: Monday, April 24, 1:00 PM

Where?: lecture hall, Department of Dermatology, Von-Esmarch-Str. 58, 48149 Münster


Crosstalk of (neuro)inflammation and cardiovascular dysfunction

Thu, 20/04/2017

Mainz. The Centre for Research on Thrombosis and Hoeostasis is proud to welcome Daniela Carnevale, PhD at its Wednesday’s Seminar.
Dr. Carnevale is assistant professor at the Department of Molecular Medicine of Sapienza University Rome; her research focusses on the crosstalk of (neuro)inflammation and cardiovascular dysfunction. She will give a talk on ‘Neuroimmune mechanisms in hypertension’.

When?: Wednesday, April 26, 5 p.m.

Where?: seminar room, building 207, Mainz University clinic

Daniela Carvale’s CV


Retinopathy in neuromyelitis optica – A lecture by Alexander Brandt

Thu, 23/03/2017

Munich. The Department of Neurology at TU Munich welcomes Dr. Alexander Brandt scientist at the NeuroCure Clinical Research Center, Charité Berlin for a lecture entitled “Retinopathy in neuromyelitis optica spectrum disorders: a longitudinal study

When?: Wednesday, 5th April 2017, 6:00-7:30 PM

Where?: library, 4th floor Neuro-Kopf-Zentrum, Klinikum rechts der Isar


SFB Scientists reprogram skin cells to brain cells to facilitate neurological research

Thu, 16/03/2017

SFB scientists Prof. Tanja Kuhlmann und Dr. Marc Ehrlich generate oligodendrocytes from skin cells (photo: FZ/E. Deiters-Keul)

Münster. (mfm/jr) Whether it be math, writing, reading or learning a new language: brain cells give us astonishing brainpower every day. When these cells are damaged by neurological diseases, cells cannot be simply sampled and analyzed in a petri dish. Scientists from the University of Münster and the Max Planck Institute for Molecular Biomedicine developed a new protocol to generate their brain cells of interest, oligodendrocytes, from skin. The team in Münster belongs to the few labs worldwide that have established this technique successfully in their lab; however the team in Münster can do this now much faster and more efficiently – with significant benefit for research.

Comparable to the insulation of wires that prevent short circuits, the axonal processes of neurons are covered by a lipid-rich sheath that allows the rapid transmission of nerve impulses. In Multiple Sclerosis and other neurological diseases this insulation – the so-called myelin sheath which is formed by oligodendrocytes – is destroyed. Despite intensive research efforts, there is still no cure for these diseases of the central nervous system as scientists still do not know enough about the underlying disease mechanisms. One reason for this lack of knowledge is the limited access to brain cells from patients due to the inaccessibility of the human brain and the high risk for patients undergoing brain surgery.

In order to obtain access and analyze human nerve cells regardless of this major obstacle, researchers from the Institute of Neuropathology in Münster chose the “do-it-yourself” option. Dr. Marc Ehrlich and Prof. Tanja Kuhlmann, both members of the SFB 128, developed in close collaboration with Prof. Hans Schöler and his colleagues from the Max Planck Institute for Molecular Biomedicine in Muenster a new method to generate human oligodendrocytes from patients without the need to access the human brain. To accomplish this, the scientists took skin cells from patients and reprogrammed them into induced pluripotent stem cells. These stem cells were subsequently turned into oligodendrocytes using a combination of proteins. “The three proteins we used regulate processes within the cell and start a maturation program that turns stem cells into oligodendrocytes”, explains neuropathologist Prof. Tanja Kuhlmann the procedure.

By this means, oligodendrocytes very similar to those in the human brain form a new insulation layer in less than one month.
Alternative techniques available so far require 70 to 150 days to generate human oligodendrocytes from stem cells. Due to its high efficiency this new method enables researchers for the first time to obtain large amounts of human oligodendrocytes and test large libraries of drug candidates on these cells. “This helps us to better investigate the underlying pathogenic mechanisms of complex diseases such as Multiple Sclerosis and will hopefully facilitate the identification of new therapeutic agents in the future”, Dr. Marc Ehrlich points out the impact of their findings for future research projects.


11th CiM-IMPRS graduate school meeting in Muenster 2017

Thu, 16/03/2017

Münster. The Cluster of Excellence “Cells in Motion” hosts the 11th CiM-IMPRS Graduate School Meeting on April 26-28, 2017 at the Max Planck Institute for Molecular Biomedicine in Muenster.

This international scientific meeting is organised by the PhD students of the Cells-in-Motion and the International Max Planck Research School Graduate Program.

The purpose of this three day meeting is to bring together international experts in the fields of Cell Migration, Vasculature, Development and Disease, Optical tools and Imaging, Biophysics and Physiology in order to create an interdisciplinary atmosphere with a multitude of formal and informal interactions.

For more information about our exciting program, please check the CiM website.

Registration is now open and free of charge. Registration deadline: March 26, 2017


How the understanding of MS pathways leads to the development of new therapies

Mon, 13/03/2017

Muenster. The pathways that lead to neurodegeneration in MS are still not fully known. Yet, the better they are understood, the better new MS therapies can interfere with these mechanisms of disease. In her lecture Dr. Susan Goelz, advisor on translational science at Oregon Health and Science University, will focus on the putative pathways of neurodegeneration in MS and discuss how scientist might use them for the development of new therapies. After having worked as a director of pharmaceutical companies for many years, Dr. Goelz is now an advisor associated to the Department of Neurology, Oregon.
Place: Conference Room 603, level 05 western tower, University Hospital, Albert-Schweitzer-Campus 1, Building A 1, Muenster
Time: Wednesday, May 17, 6:15 PM


Brownbag Lunch lecture by Hanna Gerwien

Tue, 07/03/2017

Muenster. SFB 128 researcher Hanna Gerwien will present her work within the Cells in Motion Brownbag Lunch. When listening to her talk on “Imaging MMP activity in EAE and MS”, all attendees will be provided with free lunch.

When?: Conference Room 403, level 05 eastern tower, University Hospital, Albert-Schweitzer-Campus 1, Building A 1, Muenster

Where?: Thursday, March 23, 12 h


Lecture by Christian Münz

Tue, 07/03/2017

Mainz. The FZI Mainz welcomes Prof. Christian Münz, PhD, from the Institute of Experimental Immunology at Zurich University will give a lecture entitled “Infection and immune control of a human tumor virus in vivo”.

When?
: Thursday, March 9, 5:15 PM

Where?: seminar Room 2, Building 708, Johannes Gutenberg University’s medical campus


Processing of language in the brain

Tue, 07/03/2017

Frankfurt. Neurosciences as well as linguistics are both focusing on the smallest possible elements – either in the brain or in the language. David Poeppel, renowned professor of psychiatry and neurosciences, connects brain research and language by analyzing how the smallest elements of language are processed in the brain. He is invited speaker at the rmn2 lecture. His talk “Die Elementarteilchen der Sprache und ihre Verarbeitung im Gehirn” (in German) will be introduced by Prof. Dr. Birgitta Wolff, president of the Goethe University Frankfurt, Prof. Dr. Georg Krausch, president of the JGU Mainz and Prof. Dr. Mira Mezini, vice president of research, Darmstadt
Where?: Universitätsklinikum Frankfurt, Building 23, Lecture Hall 3, Theodor-Stern-Kai 7, 60590 Frankfurt
When?: Monday, March 13, 5:00 PM


From circuits to behaviour in the insular cortex

Tue, 07/03/2017

Planegg. The International Lecture Series entitled “From biological structures to neuronal circuits” continues in March 2017. For the upcoming weeks, the International Max Planck Research School is welcoming Natine Gogolla (MPI of Neuobiology) giving a lecture entitled „From circuits to behaviour in the insular cortex“ .
When?: Thursday, March 9, 5:00 PM
Where?: main lecture hall, T-building, Am Klopferspitz 18


The role of ubiquitin in immunity

Mon, 06/02/2017

Mainz. “Regulating Ubiquitination and Disease” is the topic of Averil Mas lecture on 9th February 17 in Mainz.
When?: Thursday, 02.02.2017, 17:15 bis 19:00
Where?: University Medical Center, Langenbeckstr. 1, Mainz Room: SR2
Prof. Ma is head of a reseach lab at the Helen Diller Family Comprehensive Cancer Center in San Francisco, USA. His research group studies mechanisms by which ubiquitin dependent proteins regulate cellular activation and survival.


Hartmut Wekerle explains the initiation of MS

Tue, 31/01/2017

Mainz. The FZI/FTN lecture series welcomes MS researcher Prof. Dr. Hartmut Wekerle (Munich) giving a talk entitled “Genesis – on the initiation of MS”. As emeritus director at the Max Planck Institute (MPI) of Neurobiology in Munich Prof. Wekerle has been honored with a senior professorship donated by the Hertie foundation which enables him to continue his distinguished and outstanding research on the early events triggering brain specific autoimmune responses. In his career Prof. Wekerle has been awarded several prices, among them the Charcot Award (2001) and the Louis D Award (2002). He has been nominated member of the German Academy of Natural Scientists (Leopoldina) in 2002.

When?: Thursday, 02.02.2017, 17:15 bis 19:00
Where?: seminar room 2, University Medical Center, Langenbeckstr. 1


Imaging multiple sclerosis – lecture by Prof. Sven Shippling

Mon, 23/01/2017

Muenster. The Department of Neurology proudly presents Prof. Dr. Sven Schippling’s lecture on “Multiple Sclerosis phenotyping using multimodal imaging (MRI and OCT)”

Date: January 11th, 2016
Time: 6:15 p.m.
Place: Conference Room (05.603), Western Tower, University Clinic Muenster,
Albert-Schweitzer-Campus 1, Building A 1

Prof. Schippling is principal investigator and co-director of the Clinical Research Priority Program Multiple Sclerosis (CRPP MS) a joint venture of the University Hospital Zurich (USZ), the University of Zurich (UZH), the ETH Zurich (ETH) and the Paul-Scherrer-Institute in Villingen (PSI). His work is focusing on the characterization of pathogenetically distinct phenotypes of MS by structural MRI imaging in combination with optical coherence tomography. More information on Prof. Schoppling’s work can be found on:
http://www.multiplesclerosis.uzh.ch/en/coretopics/pschippling.html.


Prof. Florian Bassermann speaks in Mainz

Mon, 09/01/2017

Mainz. The Molecular Signaling Unit at the Research Center for Immunotherapy (FZI) and the University Cancer Center (UCT) of the University Medical Center, Mainz proudly present 2017´s first Biomedical Research Seminar in Oncology (kindly sponsored by Merck)

Speaker: Prof. Dr. Florian Bassermann, III. Medizinische Klinik, Klinikum Rechts der Isar der Technischen Universität München
Title: “The Ubiquitin Proteasome System – Role in the Pathogenesis, Evolution and Therapy of B-Cell Malignancies”
Time: Wednesday, 18.01.2017, 5 pm
Place: JGU, Medical Campus Langenbeckstraße 1, Building 706, Lecture Hall

Prof. Bassermann is an acknowledged expert and an emerging leader in the field of hematological malignancies such as multiple myeloma and lymphoma. His research is aimed at elucidating principles of ubiquitin-dependent signaling in fundamental and cancer relevant cellular functions such as cell cycle control, DNA repair, transcription, protein synthesis, cell differentiation and apoptosis. The group works towards the identification of new therapeutic targets and guides the development of rationally designed targeted therapies and biomarkers.
As an example, his group has recently published work on the deubiquitinase Usp9x and its involvement in mediating resistance to anti-tubulin chemotherapeutics in aggressive B-cell lymphoma in EMBO Mol Med.

More information about Prof. Bassermann´s research can be found under:
http://www.med3.med.tum.de/forschung/Grundlagenforschung/Zellzyklusregulation/index.html
http://www.bassermann-lab.med3.med.tum.de/index.php?id=5&L=0
http://www.mri.tum.de/node/3539


Lecture: How T cells talk to phagocytes

Wed, 04/01/2017

Muenster. The Department of Neurology welcomes Prof. Dr. Burkhard Becher (Zurich) for a Lecture entitled “Tissue Inflammation: How T cells talk to phagocytes!”

Date: January 11, 2017
Time: 6:15 p.m.
Place: large conference room, Level 05 west in the central clinics building, Albert-Schweitzer-Campus 1, 48149 Muenster

Prof. Becher is co-chair of the Institute of Experimental Immunology at Zurich University. His research aims at understanding the development of tissue-specific autoimmunity and the interaction of the nervous system with the immune system under inflammatory conditions. His work has been recognized by several research awards, among them the Sobek Junior Research Award (2004).


Zellkraftwerk´s chipcytometry

Wed, 04/01/2017

Mainz– The Research Center for Immunotherapy (FZI) Mainz is offering a very special lunch seminar about a new technique: Christoph Enz, Bramsche (Cenibra) will talk about:
“Zellkraftwerk´s chipcytometry and how it changes processes and possibilities for biomarker analyses in preclinical and clinical trials”
When?: January 17, 11:30 – 13:00
Where?: Lecture Hall, building 706, University Medical Center, Langenbeckstr. 1

The analysis of cellular biomarkers using cytometry is broadly applied, however limited by restrictions in the number of markers and the requirements for speedy sample processing. Zellkraftwerk´s chipcytometry is opening new dimensions with the potential for large multiplex analyses even from small sample volumes, it eliminates the need to process cellular samples within days, and it allows the re-interrogation of given samples for new markers even after extended periods of time. Basic principles of the method and the services offered will be addressed in this short talk together with real life case studies.

After the seminar guests will have time to discuss with Dr. Bramsche.


Lost in translation?!

Fri, 02/12/2016

Münster Prof. Mathias Bähr, Director of the Department of Neurology, University of Göttingen, is an expert on cellular and molecular mechanisms of neuronal dysfunction and neuronal cell death in animal models of the respective disorders; his ultimate goal is to detect new targets for therapeutic neuroprotective intervention. But how can research in this field be translated into patient care? This question will be tacked in Prof. Bähr’s lecture within the neurological seminar Muenster
Place: Conference Room 05.603, Main Building, University Clinic Muenster
Time: Wednesday, December 21, 6:15 PM


High ranking guests at the FTN and FZI lecture series in Mainz

Fri, 02/12/2016

Mainz – Within the FTN and FZI lecture series Mainz welcomes high-ranking experts in the field of neuroimmunology who will present their research in the upcoming months:

Prof. Alexandre Prat, MD PhD, Head of Neuroscience, CHUM, Professor of Neuroscience, Université de Montréal – “Vascular Determinants of Lesion Formation in Multiple Sclerosis”
Place: Seminar Room 2, Building 708, JGU’s medical campus
Time: Tuesday, December 13, 5:00 PM

Prof. Ulrich Steinhoff, PhD Head of the Institute of Medical Microbiology and Hygiene, Marburg – “The Influence of Nutrition and Microbiota on the Mucosal Immune System”
Place: Seminar Room 1, Building 708, JGU’s medical campus
Time: Thursday, December 15, 5:15 PM


Idiopathic inflammatory myopathies – scientific and clinical update

Fri, 02/12/2016

Münster – The Department of Neurology Muenster welcomes one of its scientists for a lecture on December 14: Tobias Ruck, MD from the working group of Profs. Heinz Wiendl and Sven Meuth will give a state of the art report on research and therapy of idiopathic inflammatory myopathies (lecture in German)
Place: Conference Room 05.603, Main Building, University Clinic Muenster
Time: Wednesday, December 14, 6:15 PM


Lecture on protein pattern formation

Fri, 02/12/2016

Mainz The International Max Planck Research School (IMPRS) welcomes Prof. Petra Schwille, PhD, who will talk about her research on “Protein Pattern formation”
Place: small lecture Hall, T-building, Max Planck Institute of Biochemistry
Time: Thursday, December 8, 5:00 PM


Featured publication: Imaging matrix metalloproteinase activity in multiple sclerosis as a specific marker of leukocyte penetration of the blood-brain barrier

Wed, 23/11/2016

Münster – The enzymes gelatinase A/matrix metalloproteinase-2 (MMP-2) and gelatinase B/MMP-9 are essential for induction of neuroinflammatory symptoms in experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis (MS). In the absence of these enzymes, the disease does not develop. SFB128 scientists of Prof. Dr. Lydia Sorokin’s group, therefore, investigated the cellular sources and relative contributions of MMP-2 and MMP-9 to disease at early stages of EAE induction. They demonstrated that MMP-9 from an immune cell source is required in EAE for initial infiltration of leukocytes into the central nervous system and that MMP-9 activity is a reliable marker of leukocyte penetration of the blood-brain barrier.
The neuroscientists then developed a molecular imaging method to visualize MMP activity in the brain using fluorescent- and radioactive-labeled MMP inhibitors (MMPis).
By using radioactive MMP ligand in EAE animals the Muenster neuroscientists produced positron emission tomography (PET) images of MMP activity in patients with MS.
In contrast to traditional T1-gadolinium contrast-enhanced MRI, MMPi-PET enabled tracking of MMP activity as a unique feature of early lesions and ongoing leukocyte infiltration.
MMPi-PET therefore allows monitoring of the early steps of MS development and provides sensitive, noninvasive means of following lesion formation and resolution in murine EAE and human MS, the neuroscientists conclude. Their work was part of the SFB projects B03 and Z02.


Research into “accident black spots“: new hypothesis on the origins of centres of inflammation in multiple sclerosis

Mon, 21/11/2016

Münster (mfm/sk-sm) – The scenario resembles a serious motor accident: a car has spun out of control, breaches the central crash barrier and collides with the oncoming traffic. In the case of multiple sclerosis, harmful T-cells break through the protective blood-brain barrier and thus penetrate into the central nervous system (CNS), where they trigger a destructive inflammation. What’s special about this is that evidently the CNS also has “accident black spots” – in other words, places where an especially high number of centres of inflammation are be found. Neuro-immunologists at Münster University have now found out why this is so.
“The decisive factor is the interplay between the immune cells and the endothelium – a protective covering which is usually particularly non-permeable, demarcates our blood vessels and is also found at the blood-brain barrier,” explains Dr. Luisa Klotz, a lecturer, research team leader and senior physician at the Department of General Neurology at Münster University Hospital. In the case of multiple sclerosis the destructive immune cells have found a way to attack the endothelium directly and thus contribute to causing damage (lesions) in the brain. What was hitherto unclear was why certain regions are affected more often in the process while others remain protected.

PD Dr. Luisa Klotz and Ivan Kuzmanov at work in the laboratory (Photo: FZ/UKM)

PD Dr. Luisa Klotz and Ivan Kuzmanov at work in the laboratory (Photo: FZ/UKM)

Observations carried out on mice pointed out the way to a solution for Klotz and her team. The diseased animals originally had centres of inflammation only at places typical of MS lesions. After the researchers had switched off the inhibiting molecule B7H1 – which helps to keep the immune system in balance – the state of the disease in the animals deteriorated. Centres of inflammation were now to be found in other areas of the brain not normally affected. These new centres arose because the immune cells in this model triggered greater damage to the endothelial protective covering. As a result, the way was open to new areas of the brain. “Such an impairment of the endothelium’s function is a necessary – if not perhaps the only – condition for inflammatory lesions to arise. The underlying mechanisms of this impairment had not been known up to this point,” says Prof. Heinz Wiendl, Director of the General Neurological Clinic.
With their discovery the neuro-immunologists have also proved for the first time why even punctual changes in certain immune-regulatory molecules – as in the case of B7H1 here – can accelerate or slow down the destructive effect of the immune cells to such an extent. To return to the car metaphor: the speed limit on roads is just like the work on B7H1 for the Münster neuro-immunologists. “We have to use the properties of proteins such as this one to reduce the damage which the cells do in the nervous system,” is how doctoral student Ivan Kuzmanov explains the promising approach which he and his colleagues have adopted in the research they are currently engaged on. At the same time, however, he warns against any premature hopes: “We’re still a long way from here to producing medicine to treat MS,” he says.


1st seminar on neurostimulation in Mainz

Fri, 11/11/2016

SFB 128 principal investigators Sergiu Groppa and Muthuraman Muthuraman are hosting the 1st seminar on invasive and non-invasive neurostimulation methods at Mainz University taking place on November 17 and 18. In this scientific meeting several speakers will present an introduction to the different modalities like transcranial magnetic (TMS) and direct current stimulation (tDCS), as well as invasive stimulation techniques like deep brain stimulation (DBS). They will discuss the different applications of these techniques within the existing theoretical background and will provide algorithms for the use of these methods in research and clinical practice. Further information regarding the program, abstracts and registration can be found here.


Milestone in MS research: neuroimmunologists find cause of deficit in body’s own immune system

Tue, 25/10/2016

Within a project of the SFB 128, scientists from the universities in Münster and Munich have discovered what precisely goes wrong in the body in the case of multiple sclerosis (MS). At the same time the neuroscientists were able to demonstrate that for MS, which occurs in bouts, there is a therapy which is tailor-made to eliminate the deficit. More Information . . .


Symposium on Microbiota in Mainz on 05 Sep 2016

Fri, 12/08/2016

The Center for Thrombosis and Hemostasis (CTH) and the Research Center for Immunotherapy (FZI) Mainz have organized a symposium entitled “The indigenous microbiota Impact on immunity, vascular physiology & cardiovascular disease” taking place at Mainz University on September 5th – 6th, 2016. The conference brings together leading experts in the field of host microbial interactions with a clear focus on immunity, vascular physiology and cardiovascular disease to discuss novel
aspects and future research directions. Further information regarding the program, abstracts and registration can be found on the symposium’s flyer.


Joint SFB Meeting: Autoinflammation Breaks Barriers, Münster 20-22 Nov 2016

Fri, 12/08/2016

After a successful conference in 2014, we are pleased to announce that there will be a second international symposium on “Autoinflammation Breaks Barriers” taking place in Muenster.

Scientists are cordially invited to listen to scientific lectures and to present their abstracts in the Max Planck Institute for Molecular Biomedicine, Münster, on November 20-22, 2016. This is a joint conference of the Collaborative Research Center 1009 (SFB 1009; “Breaking Barriers: Immune cells and pathogens at cell/matrix barriers”), AID-NET (“Autoinflammatory disorders in children: Genetics, disease mechanisms, diagnostic markers, and therapeutic targets”) and our Collaborative Research Center TR 128.
Further information regarding the program, abstracts and registration can be found on the conference flyer.


18 July 2016: Nir Gov speaks about cell motility

Mon, 18/07/2016

On the 18 July 2016, Nir Gov from the Faculty of Chemistry in Revohot/Israel will come to Muenster to give a lecture on a “Theoretical model for persistant and oscillatory cell motility”. More information can be found here.


11 July 2016: Lecture of Christoph Rademacher in Muenster

Wed, 06/07/2016

On the 11 July 2016, Christoph Rademacher from the Max Plack Institute Potsdam will hold a lecture entitled “Ligand-based targeted delivery to C-type lectin receptors on immune cells” as part of the Muenster lecture series “Pioneers of cell dynamics and imaging”, organized by the excellence cluster Cells in Motion. For more information, you can have a look at the website.


Lecture: Prof. Emmanuel Flamand Roze on 5th July in Mainz

Mon, 04/07/2016

Within the FTN seminar series, Prof. Emmanuel Flammand Roze from the Marie Curie University in Paris has been invited by Prof Sergiu Groppa to talk about “Lateralization of motor control and neurodevelopment: the mirror movements paradigm”. The lecture will be in the lecture hall of building 706, starting at 6:00pm. Download the flyer:


Stipend for International Cooperation with Turkey (Project B08)

Fri, 04/03/2016

Dr. Atay Vural has been awarded a stipend by the Alexander von Humboldt Foundation to spend time in the group of Prof. Edgar Meinl to conduct research into MOG-Ak, which is part of the work done in the CRC-TR128 B08 project. After Dr. Vural’s stay in Prof. Meinl’s group, he will return to his home country of Turkey, where he will employ the techniques learnt in Germany in further research projects.


Two young researchers from CRC TR128 awarded Helmut Bauer Prize 2015

Fri, 04/03/2016

Sarah Laurent und Franziska Thaler, scientists working on the B08 project of the CRC TR128, have been awarded the Helmut Bauer Prize 2015 for young researchers for their work on the survival, regulation and activation of B cells in multiple sclerosis (see publications below). More information on this prize can be found in this press release (in German).

Laurent et al. γ-Secretase directly sheds the survival receptor BCMA from plasma cells Nat Commun 2015 6:7333

Hoffmann et al. The immunoregulator soluble TACI is released by ADAM10 and reflects B cell activation in autoimmunity J Immunol 2015 194(2):542-52

 


Lecture: Prof. Ranieri Cancedda on 2 February 2016 in Mainz

Tue, 02/02/2016

Prof. Ranieri Cancedda (Dept. of Neuroscience and Brain Technologies, University of Genova) will present the lecture Cellular environment: implications for brain development and maldevelopment

02.02.2016, 18:00: Lecture Theater, Building 706, University Medical Center Mainz


CRC-TR-128 Retreat in Münster, 4-5 February 2016

Thu, 28/01/2016

The next Retreat of the CRC-TR-128 will be held in Münster on 4-5 February 2016. Principal investigators and members will be meeting to present and discuss the progress and outlook of their projects.


Lecture: Dr. Elisabeth Binder on 27 January 2016 in Munich

Wed, 27/01/2016

Dr. Elisabeth Binder (Max-Planck-Institut für Psychiatrie, München) will present the lecture Molekulare Mechanismen von Gen x Stress Interaktionen

27.01.2016, 18:00: Klinikum rechts der Isar der TU-Munich, Neuro-Kopf-Zentrum Bibliothek, 4. OG


Heinz Wiendl awarded Sobek Prize for MS research

Wed, 27/01/2016

Prof. Heinz Wiendl, Co-Speaker of the CRC-TR-128, has been awarded the prestigious Sobek Research Prize 2015 for his contributions to research into multiple sclerosis. More information can be found in this press release (in German)


Lecture: Prof. Erich Schmutzhard on 23 January 2016 in Munich

Sat, 23/01/2016

Prof. Erich Schmutzhard(Universitätsklinik für Neurologie, Medizinische Universität Innsbruck) will present the lecture Infektionen des ZNS

23.01.2016, 18:00: Klinikum rechts der Isar der TU-Munich, Neuro-Kopf-Zentrum Bibliothek, 4. OG


Lecture: Prof. Britta Engelhardt on 19 January 2016 in Mainz

Tue, 19/01/2016

Prof. Britta Engelhardt (Immunobiology, University of Bern) will present the lecture How brain barriers control immune cell entry into the CNS

19.01.2016, 18:00: Lecture Theater, Building 706, University Medical Center Mainz


Lecture: Dr. David Stellwagen on 1 December 2015 in Mainz

Tue, 01/12/2015

Microglia TNF limits drug-induced plasticity in the striatum, Dr. David Stellwagen (Neurology & Neurosurgery, McGill University, Montreal)

01.12.2015, 18:00: Building 706, University Medical Center Mainz


Lecture: Prof. Reinhold Förster on 26 November 2015 in Mainz

Thu, 26/11/2015

How cytotoxic T cells kill virus-infected cells in vivo, Prof. Reinhold Förster (Immunology, University of Hannover)

26.11.2015, 17:15: Lecture Theater, Building 706, University Medical Center Mainz


Lecture: Dr. Johanna Scheuermann on 26 November 2016 in Munich

Thu, 26/11/2015

Regulation of Gene Expression by long non-coding RNAs, Dr. Johanna Scheuermann (Ludwig-Maximilians-Universität München)

26.11.2015, 17:00: Main Lecture Hall, T-building, Max Planck Institute of Biochemistry, Munich


Lecture: Dr. Boris Pfander on 3 December 2015 in Munich

Tue, 24/11/2015

DNA Replication Control – Once, But Only Once, Dr. Boris Pfander (MPI of Biochemistry),

03.12.2015, 17:00: Small Lecture Hall, T-building, Max Planck Institute of Biochemistry, Munich


Lecture: Prof. Karl-Peter Hopfner on 19 November in Munich

Thu, 19/11/2015

Genome Maintenance, Prof. Karl-Peter Hopfner (Ludwig-Maximilians-Universität München)

19.11.2015, 17:00: Main Lecture Hall, T-building, Max Planck Institute of Biochemistry, Munich


Lecture: Dr. Alexander Groh on 17 November in Mainz

Tue, 17/11/2015

Thalamus and Corticothalamic Interactions during Sensory Processing, Dr. Alexander Groh (Institute of Neuroscience/Neuronal Cell Biology, Technische Univerisität München)

17.11.2015, 18:00: Lecture Theater, Building 706, University Medical Center Mainz


Münster will host NeuroVisionen 11 & 3rd Neuroinflammation Symposium, November 13–14, 2015

Fri, 13/11/2015

NeuroVisionen 11 & the 3rd Neuroinflammation Symposium Münster will take place from November 13th – 14th, 2015, under the organisation of several PIs from the CRC-TR-128 (Prof. Thomas Budde, Prof. Tanja Kuhlmann, Prof. Sven Meuth, Prof. Heinz Wiendl). (more…)


Lecture: Dr. K. Mark Ansel on 12 November in Mainz

Thu, 12/11/2015

MicroRNA regulation of lymphocyte function, Dr. K. Mark Ansel (Microbiology & Immunology, University of California, San Francisco)

12.11.2015, 17:15: Lecture Theater, Building 706, University Medical Center Mainz


Lecture: Dr. Olaf Groß on 12 November in Munich

Thu, 12/11/2015

The Inflammasome, Dr. Olaf Groß  (Technische Universität München)

12.11.2015, 17:00: Main Lecture Hall, T-building, Max Planck Institute of Biochemistry, Munich


Lecture: Prof. Konstanze F. Winklhofer on 9 November in Mainz

Mon, 09/11/2015

Ubiquitin Signaling and Mitochondrial Integrity: Implications for Neurodegenerative Diseases, Prof. Konstanze F. Winklhofer (Molekulare Zellbiologie, Ruhr University Bochum).

09.11.2015, 18:00: Lecture Theater, Building 708, University Medical Center Mainz


Lecture: Prof. Reinhard Hohlfeld on Oct. 22 in Munich

Thu, 22/10/2015

Multiple Sclerosis – Neuroinflammation Meets Neurodegeneration, Prof. Reinhard Hohlfeld (Ludwig-Maximilians-Universität München)

22.10.2015, 17:00:   Main Lecture Hall, T-building, Max Planck Institute of Biochemistry, Munich


Lecture: Dr. Jonathan Kipnis on Oct. 6 in Mainz

Tue, 06/10/2015

Dr. Jonathan Kipnis, Center for Brain Immunology and Glia, University of Virginia, will present the lecture entitled “Meningeal lymphatics, meningeal immunity, and CNS autoimmunity” at the University Medical Center Mainz on 6 October 2015 at 18:00 (Lecture Theatre, Building 706).


CRC Principal Investigator, Prof. Jacqueline Trotter, together with Prof. Thomas Mittmann, discuss the role of glial cells in neuronal signalling on Deutschland Funk radio

Thu, 04/06/2015

You can read the associated article and listen to the interview on the Deutschland Funk website or using the player below.


Lecture: Prof. Dr. Josep Dalmau on 6 May in Münster

Wed, 06/05/2015

Prof. Dr. Josep Dalmau, Catalan Institution for Research and Advanced Studies (ICREA), University of Barcelona, will present the lecture entitled “Autoimmune encephalitis” in Großer Konferenzraum Ebene 05 Westturm (Raumnummer 05.603) of the University Clinic of Münster on 6 May 2015 at 18:15.


Nina Wettschureck awarded prize for mechanistic elucidation of MS therapy

Tue, 21/04/2015

Nina Wettschureck (MPI Bad Nauheim) from the CRC-TR-128, together with Markus Schwaninger (University of Lübeck), has been awarded the Novartis prize for therapy-relevant pharmacological research. The prize, which carries a value of €10,000, was presented at the Annual Conference of the German Society for Experimental and Clinical Pharmacology and Toxicology (DGPT) on 12 March 2015 in Kiel.

More details can be found in this press release, and the research for which the prize was awarded was reported in the following publication in The Journal of Clinical Investigation:

Chen H, Assmann JC, Krenz A, Rahman M, Grimm M, Karsten CM, Köhl J, Offermanns S, Wettschureck N, Schwaninger M: Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate’s protective effect in EAE. The Journal of Clinical Investigation. doi:10.1172/JCI72151 


CRC Retreat in Münster

Mon, 30/03/2015

Thanks to all those that attended the Retreat in February in the Factory Hotel in Münster. We heard the latest on a selection of the CRC projects and there was also plenty of time for fruitful discussion and socializing in the evening.

IMG_1997IMG_1992IMG_1985


CRC scientists Nicholas Schwab and Johanna Breuer win Helmut-Bauer Young-Scientist Prize for MS research

Mon, 02/02/2015

Congratulations to the CRC Scientists Nicholas Schwab and Johanna Breuer from the Neurological Clinic of the University Hospital Münster who were awarded the Helmut-Bauer Young-Scientist Prize for MS Research. (more…)


CRC scientists discover new protection mechanism for nerve cells after they are damaged

Thu, 22/01/2015

CRC scientists from the University Medical Center Mainz, together with colleagues from the University of Virginia, have identified a new mechanism that mediates repair of nerve cells after damage to the central nervous system. (more…)


Lecture by Philip de Jager in Mainz on 03.02.2015

Wed, 21/01/2015

FTN Seminar 03.02.2015, 18:00

Speaker: Philip de Jager, Institute of Neurosciences, Harvard

Title: Translating gene discovery efforts into primary prevention and drug discovery: Multiple Sclerosis and Alzheimer’s disease

Location: Building 706, Lecture Theatre, University Medical Center Mainz


Lecture by Gurumoorthy Krishnamoorthy in Mainz on 29.01.2015

Wed, 21/01/2015

FZI Seminar 29.01.2015, 17:15

Speaker: Gurumoorthy Krishnamoorthy, MPI Martinsried

Title: “Microbiome host interactions in autoimmunity”

Location: Building 706, Lecture Theatre, University Medical Center Mainz


Lecture Hans-Christian von Büdingen in München on 02.12.2014

Fri, 12/12/2014

Speaker:          Hans-Christian von Büdingen, Multiple-Sclerosis Center, UCSF

Title:                Immune Repertoires in CNS Autoimmunity: Digging Deeper

Date/Time:       Tuesday, December 02, 2014, 5:00 p.m.

Location: MPI Martinsried


International Neuroimmunology Conference in Mainz

Fri, 05/12/2014

From 9-13 November 2014, over 1000 neuroimmunologists from all over the world met at the 12th International Congress for Neuroimmunology in Mainz. (more…)


Professorship in Neuroimmunology in Mainz

Fri, 14/11/2014

The Department of Neurology is seeking to appoint a Professor for Neuroimmunology. For a full job description and how to apply, please see here.


12th ISNI Congress/14th ESNI Course on Nov 9-13 in Mainz

Sun, 09/11/2014

We are pleased to announce that the 12th Congress of the International Society for Neuroimmunology (ISNI) will take place in Mainz on 9-13 November 2014. One session of this exciting conference will be supported by the CRC-TR-128. Directly prior to ISNI 2014, the 14th Course of the European School for Neuroimmunology will also be taking place in Mainz. 

More information about both of these events, including the scientific program and how to register can be found on the ISNI website.

ISNI_Mainz_Small


Joint SFB Meeting: Autoinflammation Breaks Barriers, Münster 6-8 Nov 2014

Thu, 06/11/2014

(more…)


Final Program for “Autoinflammation breaks Barriers” now online

Mon, 03/11/2014

The final program for the Autoinflammation breaks Barriers meeting in Münster from 6-8 November is now available online.

 


CRC Young Researchers win prizes at prestigious conferences

Fri, 26/09/2014

Congratulations to Dr. Nicholas Schwab and Dr. Tilman Schneider-Hohendorf, both from the Department of Neurology, University of Münster, who received prizes at two prestigious conferences recently! (more…)


How adhesion molecules help pathogenic T cells to find their way over the blood-brain-barrier

Tue, 16/09/2014

Münster scientists: Even a highly efficacious MS drug cannot stop certain inflammatory cells (more…)


CRC Scientist Krishnaraj Rajalingam becomes Heisenberg Professor for Cell Biology in Mainz

Mon, 21/07/2014

Congratulations to Krishnaraj Rajalingam (Project B9) who has received a prestigious Heisenberg Professorship for cell biology at the Institute for Immunology of the University Medical Center of the Johannes Gutenberg University Mainz. This is the first such professorship for the JG University of Mainz. Further details can be found here.


CRC Retreat in Munich

Fri, 23/05/2014

Thanks to all those who attended the CRC Retreat in Munich in May. As well as having great weather, there were also excellent scientific talks and lively discussion during the poster session and in the Biergarten afterwards.

Special thanks go to the organizer Jutta Marks, who did a fantastic job in making this such an enjoyable meeting for all concerned.

Retreat Munich 2014


Münster: Scientists demonstrate the influence of sunlight exposure on the incidence of autoimmune diseases

Thu, 15/05/2014

(more…)


Lecture series in Münster: Pioneers in Cell Dynamics and Imaging

Mon, 28/04/2014

Starting on April, 28th, international scientists setting milestones in cell dynamics and imaging will present their most recent scientific advances in basic and translational research (more…)


Job: Professor of Neurology in Mainz

Mon, 17/03/2014

The Department of Neurology is seeking to appoint a Professor for Neurology specializing in the area of movement disorders. Details of the position can be found here.


Lecture by Dr. Dietmar Zehn in Münster

Thu, 13/02/2014

13.02.2014, 17:00: Unraveling the biology of auto- and tumor-antigen specific T cells that escape negative selection  (more…)


Lecture by Prof. Ludwig Kappos in Münster

Wed, 05/02/2014

05.02.2014, 18:15:   Clinical trials in MS achievement: current and future challenges  (more…)


Job for Senior Physician and Research Group Leader in Mainz

Thu, 23/01/2014

The Department of Neurology, University Medical Center of the Johannes Gutenberg University Mainz, Germany, is seeking applicants for a full-time position as a senior physician and research group leader. (more…)


Lecture by Professor Dr. Triantafyllos Chavakis in Münster

Wed, 22/01/2014

22.01.2014, 18:15: Vascular inflammation in experimental autoimmune encephalomyelitis (more…)


Lecture by Professor David Miller in Munich

Wed, 22/01/2014

22.01.2014, 18:00:  The role of MRI to predict and measure long term outcome in MS (more…)


Skills Workshop in Frankfurt

Fri, 20/12/2013

Thank you to all those who attended the skills workshop “Career Options in Academia and Beyond” on 18.12.2013 in Frankfurt. (more…)


CRC Retreat in Münster

Thu, 12/12/2013

Thank you to all who attended the CRC Retreat in Münster on 28-29.11.2013. It provided a great opportunity for CRC members to meet and be updated on the progress of all research projects with lively poster sessions, interesting talks and stimulating discussion. (more…)


Videoconference of Prof. Gold’s talk

Thu, 12/12/2013

Thanks to all who participated in the videoconference of Prof. Gold’s talk in Mainz on 10.12.2013. (more…)


Lecture by Prof. Ralf Gold in Mainz

Tue, 10/12/2013

10.12.2013 18:00:  Prof. Ralf Gold, Dept. Neuroscience, Ruhr University, Bochum. (more…)


Successful videoconference of Prof. Wekerle’s talk

Fri, 22/11/2013

 

On Thursday 21.11.2013, we successfully used our new videoconferencing equipment here in Mainz to watch Prof. Hartmut Wekerle give a very interesting talk in München. Thanks to all those who helped to make this technically possible. (more…)


Lecture by Prof. Hartmut Wekerle in Munich

Thu, 21/11/2013

21.11.2013, 17:00:    Multiple Sclerosis: Remote Control of an Automimmune Brain Disease

(more…)


Lecture by Prof. David Rowitch in Munich

Tue, 15/10/2013

15.10.2013, 17.15: Myelin Development and Disease

@ Hörsaal Pavillon, Klinikum rechts der Isar der TU-München


Nature Medicine paper from Münster research groups

Fri, 16/08/2013

Bittner et al’s paper entitled Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS published in Nature Medicine is now available to be viewed here.


Lectures by Drs. Mitsdörffer and Knöferle in Munich

Mon, 22/07/2013

22.07.13 15:15: Role of B cells in CNS autoimmunity

22.07.13 16:00: Modeling Alzheimer’s Disease with Neuronal Cultures Derived from Human induced Pluripotent Stem Cells

@library of the Neuro-Kopf-Zentrums, Klinikum rechts der Isar, TU-München


Lecture by Professor Ray Guillery in Mainz

Wed, 03/07/2013

03.07.2013, 18:00: The functional connections of cortical areas @ small auditorium (Kleiner Hörsaal) of building 706, University Medical Center of the Johannes-Gutenberg University Mainz


Lecture by PD Dr Mike Wattjes in Münster

Wed, 03/07/2013

03.07.2013, 17:00: New MRI aspects of MS pathology: does gray matter?  @ Department of Neurology, Building A1, Albert-Schweitzer Campus, Münster


Lecture by Professor Michael Frotscher in Mainz

Wed, 26/06/2013

03.07.2013, 18:00: Epilepsy-induced motility of differentiated neurons @ small auditorium (Kleiner Hörsaal) of building 706, University Medical Center of the Johannes-Gutenberg University Mainz


Lecture by Professor Mikael Simons in Munich

Wed, 26/06/2013

26.06.2013, 16:00: Mechanisms of myelination and demyelination in the central nervous system @ Adolf-Butenandt Institute, LMU, Munich


Lecture by Professor Hans-Peter Hartung in Mainz

Wed, 08/05/2013

08.05.2013, 18:00: Autoimmunity in the peripheral nervous system: new pathogenic insights – new therapeutic outlooks @ small auditorium (Kleiner Hörsaal) of building 706, Universitätsmedizin Mainz


Lost in Translation? International Symposium in Munich

Tue, 26/02/2013

26.02.2013: Lost in Translation? Multiple Sclerosis and its Models @ Carl-Friedrich von Siemens Stiftung, Munich


First Meeting

Thu, 24/01/2013

24.01. – 25.01.2013: First Meeting for CRC TR-128 @ Mainz


Protective and pathogenic immunological memory

Thu, 13/12/2012

13.12.2012, 17:00: Prof. Andreas Radbruch (Deutsches Rheuma-Forschungszentrum Berlin) @ Building 401, Hörsaal der Hautklinik, Mainz


Myeloid cells of the CNS

Wed, 28/11/2012

28.11.2012, 18:00: Residents and Immigrants, Dr. Richard Ransohoff (Neuroinflammation Research Center, Mellen Center for MS Treatment and Research, USA) @ Building 706, Kleiner Hörsaal Pathologie, Mainz – also available via Livestream


International Symposium

Fri, 09/11/2012

09.11. – 10.11.2012: Neuroinflammatory diseases – focus on leucocyte trafficking and the blood brain barrier @ Parkhotel Schloss Hohenfeld, Dingbängerweg 400, Münster


Neurosymposium

Thu, 08/11/2012

08.11.2012, 13:30: Neurosymposium:The Cell Biology of CNS Development, Myelination and Multiple Sclerosi, @ Johannes Joachim Becherweg 13, HS19, Mainz