Project Area Z

Clinical translational unit

 

Z02

Clinical Translation Coordinator

Prof. Dr. Luisa Klotz
Klinik für Neurologie mit Institut für Translationale Neurologie
der Westfälischen Wilhelms-Universität Münster

Prinipal Investigators

Prof. Prof. h.c. Dr. Heinz Wiendl
Klinik für Neurologie mit Institut für Translationale Neurologie
der Westfälischen Wilhelms-Universität Münster

 
Prof. Dr. Ralf Gold
Neurologische Klinik, St.-Josef-Hospital
der Ruhr-Universität Bochum

 
Prof. Dr. Bernhard Hemmer
Neurologische Klinik und Poliklinik
Klinikum rechts der Isar
Technischen Universität München

 
Prof. Dr. Reinhard Hohlfeld
Institut für Klinische Neuroimmunologie
Ludwig-Maximilians-Universität München

 
Prof. Dr. Frauke Zipp
Klinik und Poliklinik für Neurologie
Universitätsmedizin der Johannes Gutenberg-Universität Mainz

 

 

 

News

Mon, 09/03/2020
Breakthrough: SFB scientsists explain pathomechanism of Susac Syndrome
Münster. Neuroinflammation is often associated with blood-brain-barrier dysfunction, which contributes to neurological tissue damage. In a paper published in the renowned journal Nature Communications SFB 128 scientists from Mueenster reveal the pathophysiology of Susac syndrome (SuS), an enigmatic neuroinflammatory disease with central nervous system (CNS) endotheliopathy. By investigating immune cells from the blood, cerebrospinal fluid, […]...more
Wed, 04/03/2020
The brain is less immune-priviledged than we thought
Münster. Although the CNS is immune privileged, continuous search for pathogens and tumours by immune cells within the CNS is indispensable. Thus, distinct immune-cell populations also cross the blood–brain barrier independently of inflammation/under homeostatic conditions. It was previously shown that effector memory T cells populate healthy CNS parenchyma in humans and, independently, that CCR5-expressing lymphocytes […]...more
Mon, 27/01/2020
Featured Publication: Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis
Münster. Cerebrospinal fluid (CSF) protects the central nervous system (CNS) and analyzing CSF aids the diagnosis of CNS diseases, but our understanding of CSF leukocytes remains superficial. Here, using single cell transcriptomics, SFB researchers identify a specific border-associated composition and transcriptome of CSF leukocytes. In an article published in Nature Communications, they show that multiple […]...more