News

Mon, 03/06/2019
Publication: Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects.
Muenster. For the first time scientists from the University of Münster could show that multiple sclerosis (MS) alters the energy metabolism of T cells during acute phases of disease exacerbation. Therapeutic interventions targeting the metabolism of activated T cells display new potential avenues for treatment of patients with MS affecting around 250,000 people in Germany. The […]...more
Mon, 29/04/2019
Publication: Calcium influx through plasma-membrane nanoruptures drives axon degeneration in a model of multiple sclerosis.
Munich.  Here SFB researchers from Munich use in vivo calcium imaging in a multiple sclerosis model to show that cytoplasmic calcium levels determine the choice between axon loss and survival. Calcium can enter the axon through nanoscale ruptures of the axonal plasma membrane that are induced in inflammatory lesions. Neuron doi: 10.1016/ j.neuron.2018.12.023...more
Tue, 04/12/2018
SFB 128 International Symposium
SFB 128. We are happy to announce the international Symposium of the Collaborative Research Centre 128 “Multiple Sclerosis” taking place from Sunday, September 15th, till Tuesday, September 17th, 2019 in the Rhine Main region. Full details of the event will follow....more


Mon, 02/02/2015 | CRC scientists Nicholas Schwab and Johanna Breuer win Helmut-Bauer Young-Scientist Prize for MS research

Congratulations to the CRC Scientists Nicholas Schwab and Johanna Breuer from the Neurological Clinic of the University Hospital Münster who were awarded the Helmut-Bauer Young-Scientist Prize for MS Research. They each received €2500 for their work on the effects of UVB radiation on the onset and development of multiple sclerosis, which was published in Annals of Neurology.

Breuer J*, Schwab N*, Schneider-Hohendorf T, Marziniak M, Mohan H, Bhatia U, Gross CC, Clausen BE, Weishaupt C, Luger TA, Meuth SG, Loser K and Wiendl H (2014). Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity. Ann Neuro/. 2014 May; 75(5):739-58.

A detailed press release in German can be found on the University of Göttingen webpage as well as a previous post here in English describing the research.