News

Tue, 22/10/2019
The key lies in cell metabolism: Neuroscientist and neurologist Luisa Klotz wins renowned Heinrich-Pette-Award
Münster. For the third time the renowned neuroscience award “Heinrich Pette prize” goes to Münster, as this year Luisa Klotz was rewarded with the prestigious award for neuroscience researchers and clinicians at the congress of the German Society of Neurology in Stuttgart. Neurologist and Neuroscientist Luisa Klotz received the award for her outstanding research in […]...more
Mon, 07/10/2019
Talk “Der Einfluss der Ernährung und des Darms auf die Multiple Sklerose”
Muenster. The department of neurology with Institute of Translational Neurology warmly welcomes SFB 128-PI Prof. Aiden Haghikia, leading senior physician at the Department of Neurology at Bochum University Clinic. His talk “Der Einfluss der Ernährung und des Darms auf die Multiple Sklerose” provides insights into his latest research progress in this field. Time: Wednesday, October […]...more
Mon, 03/06/2019
Publication: Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects.
Muenster. For the first time scientists from the University of Münster could show that multiple sclerosis (MS) alters the energy metabolism of T cells during acute phases of disease exacerbation. Therapeutic interventions targeting the metabolism of activated T cells display new potential avenues for treatment of patients with MS affecting around 250,000 people in Germany. The […]...more


Fri, 26/10/2018 | Featured publication: Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk

In a large multi-cohort study, performed by the International Multiple Sclerosis Genetics Consortium (IMSGC) and published in Cell Magazine, unexplained heritability for multiple sclerosis (MS) is detected in low-frequency coding variants that are missed by genome-wide association study (GWAS) analyses, further underscoring the role of immune genes in MS pathology. The IMSGC was formed in 2003 with funding from the National Multiple Sclerosis Society and published results from the first GWAS in 2007 that identified the second and third susceptibility genes known to predispose people to developing MS. IMSGC later expanded to include more research groups from more countries, receiving grants to conduct larger GWAS studies. IMSGC brings together researchers from 15 different countries, among them scientists from the SFB-CRC 128 member organizations Technische Universität München and Universitätsmedizin Mainz. A pdf of the article may be found here (restricted access)