Mon, 09/03/2020
Breakthrough: SFB scientsists explain pathomechanism of Susac Syndrome
Münster. Neuroinflammation is often associated with blood-brain-barrier dysfunction, which contributes to neurological tissue damage. In a paper published in the renowned journal Nature Communications SFB 128 scientists from Mueenster reveal the pathophysiology of Susac syndrome (SuS), an enigmatic neuroinflammatory disease with central nervous system (CNS) endotheliopathy. By investigating immune cells from the blood, cerebrospinal fluid, […]...more
Wed, 04/03/2020
The brain is less immune-priviledged than we thought
Münster. Although the CNS is immune privileged, continuous search for pathogens and tumours by immune cells within the CNS is indispensable. Thus, distinct immune-cell populations also cross the blood–brain barrier independently of inflammation/under homeostatic conditions. It was previously shown that effector memory T cells populate healthy CNS parenchyma in humans and, independently, that CCR5-expressing lymphocytes […]...more
Mon, 27/01/2020
Featured Publication: Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis
Münster. Cerebrospinal fluid (CSF) protects the central nervous system (CNS) and analyzing CSF aids the diagnosis of CNS diseases, but our understanding of CSF leukocytes remains superficial. Here, using single cell transcriptomics, SFB researchers identify a specific border-associated composition and transcriptome of CSF leukocytes. In an article published in Nature Communications, they show that multiple […]...more

Tue, 17/10/2017 | Three new CRC associates

Muenster / Mainz / Munich. The CRC is proud to welcome three scientists as new associates: Muthuraman Muthuraman (Mainz), Anneli Peters (LMU) and Gerd Meyer zu Hörste (Münster).
All three are reputable neuroimmunologists, who add their in-depth knowledge of techniques and concepts to the existing team. Dr. Muthuraman Muthuraman is head of the scientific working group on biomedical statistics and multimodal signal processing at the Department of Neurology in Mainz (head: Prof. Frauke Zipp). Dr. Anneli Peters is project leader at the working group of Emeritus Director Prof. Hartmut Wekerle, focusing on the pathogenesis of multiple sclerosis. Dr. Gerd Meyer zu Hörste heads a scientific working group on understanding the interaction between nervous and immune system at the Department of Neurology in Muenster (head: Prof. Heinz Wiendl).